diff --git a/include/wx/osx/cocoa/dataview.h b/include/wx/osx/cocoa/dataview.h
index 540b66a56c..65fc99c2b3 100644
--- a/include/wx/osx/cocoa/dataview.h
+++ b/include/wx/osx/cocoa/dataview.h
@@ -249,7 +249,7 @@ private:
 // owned by the set. Furthermore, children of the last parent are stored
 // in a linear list.
 //
-@interface wxCocoaOutlineDataSource : NSObject wxOSX_10_6_AND_LATER(<NSOutlineViewDataSource>)
+@interface wxCocoaOutlineDataSource : NSObject <NSOutlineViewDataSource>
 {
     // descriptors specifying the sorting (currently the array only holds one
     // object only)
@@ -395,7 +395,7 @@ private:
 // wxCocoaOutlineView
 // ============================================================================
 
-@interface wxCocoaOutlineView : NSOutlineView wxOSX_10_6_AND_LATER(<NSOutlineViewDelegate>)
+@interface wxCocoaOutlineView : NSOutlineView <NSOutlineViewDelegate>
 {
 @private
     // column and row of the cell being edited or -1 if none
diff --git a/include/wx/osx/cocoa/private.h b/include/wx/osx/cocoa/private.h
index 83cd34d41e..cc929ae6bf 100644
--- a/include/wx/osx/cocoa/private.h
+++ b/include/wx/osx/cocoa/private.h
@@ -336,7 +336,7 @@ public:
     - (void) setTextField:(NSTextField*) field;
     @end
 
-    @interface wxNSTextField : NSTextField wxOSX_10_6_AND_LATER(<NSTextFieldDelegate>)
+    @interface wxNSTextField : NSTextField <NSTextFieldDelegate>
     {
         wxNSTextFieldEditor* fieldEditor;
     }
@@ -346,14 +346,14 @@ public:
 
     @end
 
-    @interface wxNSSecureTextField : NSSecureTextField wxOSX_10_6_AND_LATER(<NSTextFieldDelegate>)
+    @interface wxNSSecureTextField : NSSecureTextField <NSTextFieldDelegate>
     {
     }
 
     @end
 
 
-    @interface wxNSTextView : NSTextView wxOSX_10_6_AND_LATER(<NSTextViewDelegate>)
+    @interface wxNSTextView : NSTextView <NSTextViewDelegate>
     {
     }
 
@@ -432,7 +432,7 @@ public:
 #ifdef __LP64__
     WXEXPORT
 #endif // 64 bit builds
-    @interface wxNSAppController : NSObject wxOSX_10_6_AND_LATER(<NSApplicationDelegate>)
+    @interface wxNSAppController : NSObject <NSApplicationDelegate>
     {
     }
 
diff --git a/include/wx/osx/core/private.h b/include/wx/osx/core/private.h
index c52a8e5af2..9b1c371562 100644
--- a/include/wx/osx/core/private.h
+++ b/include/wx/osx/core/private.h
@@ -20,17 +20,6 @@
 #include "wx/osx/core/cfstring.h"
 #include "wx/osx/core/cfdataref.h"
 
-// Define helper macros allowing to insert small snippets of code to be
-// compiled for high enough OS X version only: this shouldn't be abused for
-// anything big but it's handy for e.g. specifying OS X 10.6-only protocols in
-// the Objective C classes declarations when they're not supported under the
-// previous versions
-#if MAC_OS_X_VERSION_MAX_ALLOWED >= MAC_OS_X_VERSION_10_6
-    #define wxOSX_10_6_AND_LATER(x) x
-#else
-    #define wxOSX_10_6_AND_LATER(x)
-#endif
-
 // platform specific Clang analyzer support
 #ifndef NS_RETURNS_RETAINED
 #   if WX_HAS_CLANG_FEATURE(attribute_ns_returns_retained)
diff --git a/src/osx/carbon/colordlgosx.mm b/src/osx/carbon/colordlgosx.mm
index a818dde360..a22a2cc44b 100644
--- a/src/osx/carbon/colordlgosx.mm
+++ b/src/osx/carbon/colordlgosx.mm
@@ -41,7 +41,7 @@ wxIMPLEMENT_DYNAMIC_CLASS(wxColourDialog, wxDialog);
 // wxCPWCDelegate - Window Closed delegate
 // ---------------------------------------------------------------------------
 
-@interface wxCPWCDelegate : NSObject wxOSX_10_6_AND_LATER(<NSWindowDelegate>)
+@interface wxCPWCDelegate : NSObject <NSWindowDelegate>
 {
     bool m_bIsClosed;
 }
diff --git a/src/osx/carbon/utilscocoa.mm b/src/osx/carbon/utilscocoa.mm
index 60c03445e0..489aeaba56 100644
--- a/src/osx/carbon/utilscocoa.mm
+++ b/src/osx/carbon/utilscocoa.mm
@@ -494,12 +494,7 @@ CGContextRef WXDLLIMPEXP_CORE wxOSXCreateBitmapContextFromNSImage( WX_NSImage ns
 
 double wxOSXGetMainScreenContentScaleFactor()
 {
-#if (MAC_OS_X_VERSION_MAX_ALLOWED >= MAC_OS_X_VERSION_10_7)
-    if ( [ [NSScreen mainScreen] respondsToSelector:@selector(backingScaleFactor)] )
-        return [[NSScreen mainScreen] backingScaleFactor];
-    else
-#endif
-        return 1.0;
+    return [[NSScreen mainScreen] backingScaleFactor];
 }
 
 CGImageRef wxOSXCreateCGImageFromNSImage( WX_NSImage nsimage, double *scaleptr )
diff --git a/src/osx/cocoa/combobox.mm b/src/osx/cocoa/combobox.mm
index fbaec3fb74..0a4acd1190 100644
--- a/src/osx/cocoa/combobox.mm
+++ b/src/osx/cocoa/combobox.mm
@@ -24,7 +24,7 @@
 
 // work in progress
 
-@interface wxNSTableDataSource : NSObject wxOSX_10_6_AND_LATER(<NSComboBoxDataSource>)
+@interface wxNSTableDataSource : NSObject <NSComboBoxDataSource>
 {
     wxNSComboBoxControl* impl;
 }
diff --git a/src/osx/cocoa/filedlg.mm b/src/osx/cocoa/filedlg.mm
index 9e439b9ab8..540358f757 100644
--- a/src/osx/cocoa/filedlg.mm
+++ b/src/osx/cocoa/filedlg.mm
@@ -52,7 +52,7 @@
 // then the delegate method - (BOOL)panel:(id)sender shouldShowFilename:(NSString *)filename will have to
 // be implemented
 
-@interface wxOpenPanelDelegate : NSObject wxOSX_10_6_AND_LATER(<NSOpenSavePanelDelegate>)
+@interface wxOpenPanelDelegate : NSObject <NSOpenSavePanelDelegate>
 {
     wxFileDialog* _dialog;
 }
diff --git a/src/osx/cocoa/listbox.mm b/src/osx/cocoa/listbox.mm
index 0eb49dd569..7966d70223 100644
--- a/src/osx/cocoa/listbox.mm
+++ b/src/osx/cocoa/listbox.mm
@@ -30,7 +30,7 @@
 
 class wxListWidgetCocoaImpl;
 
-@interface wxNSTableDataSource : NSObject wxOSX_10_6_AND_LATER(<NSTableViewDataSource>)
+@interface wxNSTableDataSource : NSObject <NSTableViewDataSource>
 {
     wxListWidgetCocoaImpl* impl;
 }
@@ -50,7 +50,7 @@ class wxListWidgetCocoaImpl;
 
 @end
 
-@interface wxNSTableView : NSTableView wxOSX_10_6_AND_LATER(<NSTableViewDelegate>)
+@interface wxNSTableView : NSTableView <NSTableViewDelegate>
 {
 }
 
diff --git a/src/osx/cocoa/menu.mm b/src/osx/cocoa/menu.mm
index 562efe75d4..eb52113acc 100644
--- a/src/osx/cocoa/menu.mm
+++ b/src/osx/cocoa/menu.mm
@@ -58,7 +58,7 @@
 // and under 10.4, we are not getting a 'close' event however...
 #define wxOSX_USE_NEEDSUPDATE_HOOK 1
 
-@interface wxNSMenuController : NSObject wxOSX_10_6_AND_LATER(<NSMenuDelegate>)
+@interface wxNSMenuController : NSObject <NSMenuDelegate>
 {
 }
 
diff --git a/src/osx/cocoa/nonownedwnd.mm b/src/osx/cocoa/nonownedwnd.mm
index a13efdabbf..97186983b1 100644
--- a/src/osx/cocoa/nonownedwnd.mm
+++ b/src/osx/cocoa/nonownedwnd.mm
@@ -91,19 +91,11 @@ bool shouldHandleSelector(SEL selector)
 
 }
 
-
-#define wxHAS_FULL_SCREEN_API (MAC_OS_X_VERSION_MAX_ALLOWED >= MAC_OS_X_VERSION_10_7)
-
-#if wxHAS_FULL_SCREEN_API
-
 static bool IsUsingFullScreenApi(WXWindow macWindow)
 {
-    return [macWindow respondsToSelector:@selector(toggleFullScreen:)]
-        && ([macWindow collectionBehavior] & NSWindowCollectionBehaviorFullScreenPrimary);
+    return ([macWindow collectionBehavior] & NSWindowCollectionBehaviorFullScreenPrimary);
 }
 
-#endif
-
 //
 // wx category for NSWindow (our own and wrapped instances)
 //
@@ -313,7 +305,7 @@ static NSResponder* s_formerFirstResponder = NULL;
 // controller
 //
 
-@interface wxNonOwnedWindowController : NSObject wxOSX_10_6_AND_LATER(<NSWindowDelegate>)
+@interface wxNonOwnedWindowController : NSObject <NSWindowDelegate>
 {
 }
 
@@ -326,9 +318,7 @@ static NSResponder* s_formerFirstResponder = NULL;
 - (void)windowDidDeminiaturize:(NSNotification *)notification;
 - (BOOL)windowShouldClose:(id)window;
 - (BOOL)windowShouldZoom:(NSWindow *)window toFrame:(NSRect)newFrame;
-#if wxHAS_FULL_SCREEN_API
 - (void)windowWillEnterFullScreen:(NSNotification *)notification;
-#endif
 
 @end
 
@@ -585,8 +575,6 @@ extern int wxOSXGetIdFromSelector(SEL action );
     return true;
 }
 
-#if wxHAS_FULL_SCREEN_API
-
 // work around OS X bug, on a secondary monitor an already fully sized window
 // (eg maximized) will not be correctly put to full screen size and keeps a 22px
 // title band at the top free, therefore we force the correct content size
@@ -607,8 +595,6 @@ extern int wxOSXGetIdFromSelector(SEL action );
     }
 }
 
-#endif
-
 @end
 
 wxIMPLEMENT_DYNAMIC_CLASS(wxNonOwnedWindowCocoaImpl , wxNonOwnedWindowImpl);
@@ -1000,44 +986,32 @@ typedef struct
 
 bool wxNonOwnedWindowCocoaImpl::IsFullScreen() const
 {
-#if wxHAS_FULL_SCREEN_API
     if ( IsUsingFullScreenApi(m_macWindow) )
     {
         return [m_macWindow styleMask] & NSFullScreenWindowMask;
     }
-#endif
 
     return m_macFullScreenData != NULL ;
 }
 
 bool wxNonOwnedWindowCocoaImpl::EnableFullScreenView(bool enable)
 {
-#if wxHAS_FULL_SCREEN_API
-    if ( [ m_macWindow respondsToSelector:@selector(setCollectionBehavior:) ] )
+    NSUInteger collectionBehavior = [m_macWindow collectionBehavior];
+    if (enable)
     {
-        NSUInteger collectionBehavior = [m_macWindow collectionBehavior];
-        if (enable)
-        {
-            collectionBehavior |= NSWindowCollectionBehaviorFullScreenPrimary;
-        }
-        else
-        {
-            collectionBehavior &= ~NSWindowCollectionBehaviorFullScreenPrimary;
-        }
-        [m_macWindow setCollectionBehavior: collectionBehavior];
-
-        return true;
+        collectionBehavior |= NSWindowCollectionBehaviorFullScreenPrimary;
     }
-#else
-    wxUnusedVar(enable);
-#endif
+    else
+    {
+        collectionBehavior &= ~NSWindowCollectionBehaviorFullScreenPrimary;
+    }
+    [m_macWindow setCollectionBehavior: collectionBehavior];
 
-    return false;
+    return true;
 }
 
 bool wxNonOwnedWindowCocoaImpl::ShowFullScreen(bool show, long WXUNUSED(style))
 {
-#if wxHAS_FULL_SCREEN_API
     if ( IsUsingFullScreenApi(m_macWindow) )
     {
         if ( show != IsFullScreen() )
@@ -1047,7 +1021,6 @@ bool wxNonOwnedWindowCocoaImpl::ShowFullScreen(bool show, long WXUNUSED(style))
 
         return true;
     }
-#endif
 
     if ( show )
     {
diff --git a/src/osx/cocoa/notebook.mm b/src/osx/cocoa/notebook.mm
index 33b773b117..ead8978b54 100644
--- a/src/osx/cocoa/notebook.mm
+++ b/src/osx/cocoa/notebook.mm
@@ -29,7 +29,7 @@
 // controller
 //
 
-@interface wxTabViewController : NSObject wxOSX_10_6_AND_LATER(<NSTabViewDelegate>)
+@interface wxTabViewController : NSObject <NSTabViewDelegate>
 {
 }
 
diff --git a/src/osx/cocoa/textctrl.mm b/src/osx/cocoa/textctrl.mm
index 22fc4e7681..cb12954e4b 100644
--- a/src/osx/cocoa/textctrl.mm
+++ b/src/osx/cocoa/textctrl.mm
@@ -827,7 +827,7 @@ wxNSTextFieldControl::wxNSTextFieldControl(wxWindow *wxPeer,
 
 void wxNSTextFieldControl::Init(WXWidget w)
 {
-    NSTextField wxOSX_10_6_AND_LATER(<NSTextFieldDelegate>) *tf = (NSTextField wxOSX_10_6_AND_LATER(<NSTextFieldDelegate>)*) w;
+    NSTextField <NSTextFieldDelegate> *tf = (NSTextField <NSTextFieldDelegate>*) w;
     m_textField = tf;
     [m_textField setDelegate: tf];
     m_selStart = m_selEnd = 0;
diff --git a/src/osx/cocoa/toolbar.mm b/src/osx/cocoa/toolbar.mm
index 243b0c4d42..e5f918dbad 100644
--- a/src/osx/cocoa/toolbar.mm
+++ b/src/osx/cocoa/toolbar.mm
@@ -301,7 +301,7 @@ private:
 @end
 
 
-@interface wxNSToolbarDelegate : NSObject wxOSX_10_6_AND_LATER(<NSToolbarDelegate>)
+@interface wxNSToolbarDelegate : NSObject <NSToolbarDelegate>
 {
     bool m_isSelectable;
 }
diff --git a/src/osx/cocoa/utils.mm b/src/osx/cocoa/utils.mm
index 7faa2bc61b..d3418d9433 100644
--- a/src/osx/cocoa/utils.mm
+++ b/src/osx/cocoa/utils.mm
@@ -412,7 +412,7 @@ bool wxApp::DoInitGui()
         }
 
         appcontroller = OSXCreateAppController();
-        [[NSApplication sharedApplication] setDelegate:(id wxOSX_10_6_AND_LATER(<NSApplicationDelegate>))appcontroller];
+        [[NSApplication sharedApplication] setDelegate:(id <NSApplicationDelegate>)appcontroller];
         [NSColor setIgnoresAlpha:NO];
 
         // calling finishLaunching so early before running the loop seems to trigger some 'MenuManager compatibility' which leads
diff --git a/src/osx/cocoa/window.mm b/src/osx/cocoa/window.mm
index 91e02ed9e5..e2ead70efe 100644
--- a/src/osx/cocoa/window.mm
+++ b/src/osx/cocoa/window.mm
@@ -1755,9 +1755,7 @@ void wxOSXCocoaClassAddWXMethods(Class c)
     wxOSX_CLASS_ADD_METHOD(c, @selector(mouseEntered:), (IMP) wxOSX_mouseEvent, "v@:@" )
     wxOSX_CLASS_ADD_METHOD(c, @selector(mouseExited:), (IMP) wxOSX_mouseEvent, "v@:@" )
         
-#if MAC_OS_X_VERSION_MAX_ALLOWED >= MAC_OS_X_VERSION_10_5
     wxOSX_CLASS_ADD_METHOD(c, @selector(magnifyWithEvent:), (IMP)wxOSX_mouseEvent, "v@:@")
-#endif
 
     wxOSX_CLASS_ADD_METHOD(c, @selector(cursorUpdate:), (IMP) wxOSX_cursorUpdate, "v@:@" )
 
@@ -1870,13 +1868,8 @@ void wxWidgetCocoaImpl::SetVisibility( bool visible )
 
 double wxWidgetCocoaImpl::GetContentScaleFactor() const
 {
-#if MAC_OS_X_VERSION_MAX_ALLOWED >= MAC_OS_X_VERSION_10_7
     NSWindow* tlw = [m_osxView window];
-    if ( [ tlw respondsToSelector:@selector(backingScaleFactor) ] )
-        return [tlw backingScaleFactor];
-    else
-#endif
-        return 1.0;
+    return [tlw backingScaleFactor];
 }
 
 // ----------------------------------------------------------------------------
@@ -1884,7 +1877,7 @@ double wxWidgetCocoaImpl::GetContentScaleFactor() const
 // ----------------------------------------------------------------------------
 
 // define a delegate used to refresh the window during animation
-@interface wxNSAnimationDelegate : NSObject wxOSX_10_6_AND_LATER(<NSAnimationDelegate>)
+@interface wxNSAnimationDelegate : NSObject <NSAnimationDelegate>
 {
     wxWindow *m_win;
     bool m_isDone;