diff --git a/src/generic/listctrl.cpp b/src/generic/listctrl.cpp
index 1126d66902..2e9852802b 100644
--- a/src/generic/listctrl.cpp
+++ b/src/generic/listctrl.cpp
@@ -3040,7 +3040,7 @@ void wxListMainWindow::OnMouse( wxMouseEvent &event )
 
         size_t oldCurrent = m_current;
         bool cmdModifierDown = event.CmdDown();
-        if ( !(cmdModifierDown || event.ShiftDown()) )
+        if ( IsSingleSel() || !(cmdModifierDown || event.ShiftDown()) )
         {
             if( IsSingleSel() || !IsHighlighted(current) )
             {