diff --git a/include/wx/msw/setup0.h b/include/wx/msw/setup0.h
index 0e32f556a4..cd01827079 100644
--- a/include/wx/msw/setup0.h
+++ b/include/wx/msw/setup0.h
@@ -50,7 +50,7 @@
 // Default is 0
 //
 // Recommended setting: 0 (please update your code)
-#define WXWIN_COMPATIBILITY_2_2 1
+#define WXWIN_COMPATIBILITY_2_2 0
 
 // This setting determines the compatibility with 2.4 API: set it to 0 to
 // flag all cases of using deprecated functions.